Homo sapiens miR-21 stemp-loop UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACACCAGUCGAUGGGCUGUCUGACA "Mature sequence Accession:MIMAT0000076;ID:hsa-miR-21 Sequence(8-29) 5'-uagcuuaucagacugauguuga-3'" TCAACATCAGTCTGATAAGCTA 2'-MOE PO TCAACATCAGTCTGATAAGCTA 2'-MOE PS TCAACATCAGTCTGATAAGCTA 2'-MOE PS TCAACATCAGTCTGATAAGCTA 2'-MOE PS TCAACATCAGTCTGATAAGCTA 2'-MOE PS TCAACATCAGTCTGATAAGCTA 2'-OMe PS TCAACATCAGTCTGATAAGCTA 2'-OMe PO TCAACATCAGTCTGATAAGCTA 2'-MOE PS TCAACATCAGTCTGATAAGCTA 2'-MOE PS ucaacacagucugauaagcua 2'-OMe ++++ +++ +++ + + + + - -
<Annotation/> </Figure> <Comments>dididd</Comments> </AntiAssay> <AntiAssay AssayType="InVitro" SeriesID="sid200533" RefIDs="ref000002" Transfection_Method="lipofectamine 2000"> <Efficacy AntiID="AOs000010" RefID="ref000002" CtrlIDs="ctr000002" CellLine="Hela" AssayLevel="miRNA" AssayMethod="miRNA array" Conc="10-30 pmol ">+++</Efficacy> <Efficacy AntiID="AOs000010" RefID="ref000002" CtrlIDs="ctr000002" CellLine="A549" AssayLevel="miRNA" AssayMethod="miRNA array" Conc="10-30 pmol">++++</Efficacy> <Control CtrlID="ctr000002" CtrlType="NC" CtrlSeq="guggauauuguugccauca" AssayLevel="miRNA" AssayMethod="miRNA array" CtrlConc="10-30 pmol "/> <Figure> <Title/> <Annotation/> </Figure> <Comments/> </AntiAssay> </AntiAgent> <Reference RefID="ref000001"> <Author>Scott Davis, Bridget Lollo, Susan Freier and Christine Esau</Author> <Title>"Improved targeting of miRNA with antisense oligonucleotides" Nucleic Acids Research 2006 34 8 2294-2304 Angie M. Cheng, Mike W. Byrom, Jeffrey Shelton and Lance P. Ford Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis Nucleic Acids Research 2005 33 4 1290-1297 2006-08-27